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Old School RuneScape or OSRS Cover Image with an island and clouds in the background.
Image via Jagex Ltd

How to Craft Sanfew Serum in OSRS

Potion's class.

Old School RuneScape also known as OSRS is a MMORPG released back in 2013. As an updated sequel to the popular RuneScape game, it features a fictional world called Gielinor, a planet having multiple environments and climates. Divided into humans, vampyres, elves, monkeys, dwarves, fairies, and other races, the players interact with each other. Having a fictional theme, the game has magical serums like Sanfew.

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The Sanfew Serum has positive properties of super restore, superantipoison, and Relicym’s balm potions, which grants temporary immunity against diseases. Let’s see how you can make this amazing serum in the game.

How to Craft Sanfew Serum in OSRS

Before you craft Sanfew, you will need a super restore potion. If you are unaware, super restore is a healing potion which restores all lowered player stats, like Prayer. However, it doesn’t restore Hitpoints.

Related: Old School Runescape (OSRS): Wyrm Guide

Super Restore Recipe

To make super restore potion, you need to reach level 63 in Herblore. Once you’ve done that, combine these ingredients:

  • Snapdragon x 1
  • Vial of water x 1

Now, add one quantity of red spiders’ eggs to the Snapdragon potion you just made.

Sanfew Serum Recipe in OSRS

Before brewing the serum, you will need at least level 65 Herblore and completion of Zogre Flesh Eaters, which is a quest in the Feldip Hills area. You will also need an untradeable item called snake weed. Search the marshy jungle vines in south-west of Tai Bwo Wannai. Players can also get snake weed as a drop from Jogres and Tribesmen.

You can make Sanfew serum by adding unicorn horn dust, clean snake weed, and nail beast nails to the super restore potion you made. Note: All ingredients will have to be in a single quantity. Also, pour them in the order mentioned.


If you like this guide, check out How do you Get to Fossil Island in Old School Runescape (OSRS)? and How to Beat grotesque guardians in OSRS. Have a look at the Gamer Journalist Facebook page for latest stories on other games.

Author
Image of Anuj Gupta
Anuj Gupta
Anuj has been into video games since his childhood days. From Road Rash 1994 to the latest NFS and the entire FIFA series, Anuj has a big diary of nostalgic games. With his interest in multiple genres of video games, Anuj has also tapped his feet deep into esports. He has above 10 thousand hours in Dota 2 and plays CS:GO for fun. You can find him noodling on his guitar when he isn’t writing about games.